RIG-I-Like Receptors and Type I Interferonopathies
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چکیده
منابع مشابه
How RIG-I like receptors activate MAVS.
RIG-I and MDA5 are well-conserved cytoplasmic pattern recognition receptors that detect viral RNAs during infection and activate the type I interferon (IFN)-mediated antiviral immune response. While much is known about how these receptors recognize viral RNAs, how they interact with their common signaling adaptor molecule MAVS and activate the downstream signaling pathway had been less clear. P...
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ژورنال
عنوان ژورنال: Journal of Interferon & Cytokine Research
سال: 2017
ISSN: 1079-9907,1557-7465
DOI: 10.1089/jir.2016.0095